P073-0549 Screening compound: 2-chloro-N-(2-{1-[(4-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)benzamide

P073-0549 Screening compound: 2-chloro-N-(2-{1-[(4-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)benzamide
P073-0549 Screening compound: 2-chloro-N-(2-{1-[(4-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P073-0549
2-chloro-N-(2-{1-[(4-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P073-0549

Molecular Formula

C23H21ClN4O2 (C23 H21 ClN4 O2)

Compound Name

2-chloro-N-(2-{1-[(4-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)benzamide

IUPAC name

2-chloro-N-(2-{1-[(4-methylphenyl)methyl]-2-oxo-1H2H3H-imidazo[45-b]pyridin-3-yl}ethyl)benzamide

SMILES

Cc1ccc(CN(c2cccnc2N2CCNC(c(cccc3)c3Cl)=O)C2=O)cc1

InChI

InChI=1S/C23H21ClN4O2/c1-16-8-10-17(11-9-16)15-28-20-7-4-12-25-21(20)27(23(28)30)14-13-26-22(29)18-5-2-3-6-19(18)24/h2-12H,13-15H2,1H3,(H,26,29)

InChI Key

IICNPETVNJSTHQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27562455

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.9

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.585

Distribution Coefficient, logD

4.585

Water Solubility, LogSw

-4.61

Polar Surface Area

52.684

Acid Dissociation Constant (pKa)

12.60

Base Dissociation Constant (pKb)

0.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

P073-0549 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P073-0549 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P073-0549?
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What is the minimum amount of P073-0549 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P073-0549
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P073-0549
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P073-0549 available by request