P073-0622 Screening compound: 5-chloro-N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)thiophene-2-carboxamide

P073-0622 Screening compound: 5-chloro-N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)thiophene-2-carboxamide
P073-0622 Screening compound: 5-chloro-N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P073-0622
5-chloro-N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P073-0622

Molecular Formula

C20H16ClFN4O2S (C20 H16 ClFN4 O2 S)

Compound Name

5-chloro-N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)thiophene-2-carboxamide

IUPAC name

5-chloro-N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H2H3H-imidazo[45-b]pyridin-3-yl}ethyl)thiophene-2-carboxamide

SMILES

O=C(c(s1)ccc1Cl)NCCN(c1ncccc1N1Cc(cc2)ccc2F)C1=O

InChI

InChI=1S/C20H16ClFN4O2S/c21-17-8-7-16(29-17)19(27)24-10-11-25-18-15(2-1-9-23-18)26(20(25)28)12-13-3-5-14(22)6-4-13/h1-9H,10-12H2,(H,24,27)

InChI Key

ASVZRDMVICACLU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27562513

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.89

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.064

Distribution Coefficient, logD

4.064

Water Solubility, LogSw

-4.46

Polar Surface Area

53.703

Acid Dissociation Constant (pKa)

12.60

Base Dissociation Constant (pKb)

0.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

P073-0622 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P073-0622 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P073-0622?
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What is the minimum amount of P073-0622 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P073-0622
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P073-0622
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P073-0622 available by request