P073-0627 Screening compound: N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)quinoline-2-carboxamide

P073-0627 Screening compound: N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)quinoline-2-carboxamide
P073-0627 Screening compound: N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)quinoline-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P073-0627
N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)quinoline-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P073-0627

Molecular Formula

C25H20FN5O2 (C25 H20 FN5 O2)

Compound Name

N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)quinoline-2-carboxamide

IUPAC name

N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H2H3H-imidazo[45-b]pyridin-3-yl}ethyl)quinoline-2-carboxamide

SMILES

O=C(c1nc2ccccc2cc1)NCCN(c(nccc1)c1N1Cc(cc2)ccc2F)C1=O

InChI

InChI=1S/C25H20FN5O2/c26-19-10-7-17(8-11-19)16-31-22-6-3-13-27-23(22)30(25(31)33)15-14-28-24(32)21-12-9-18-4-1-2-5-20(18)29-21/h1-13H,14-16H2,(H,28,32)

InChI Key

NEDXOUSFSAOEOF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27562516

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.055

Distribution Coefficient, logD

4.055

Water Solubility, LogSw

-4.01

Polar Surface Area

61.015

Acid Dissociation Constant (pKa)

13.53

Base Dissociation Constant (pKb)

1.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

P073-0627 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P073-0627 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P073-0627?
Check Price and Availability of P073-0627, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P073-0627 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P073-0627
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P073-0627
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P073-0627 available by request