P073-0643 Screening compound: N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)pyrazine-2-carboxamide

P073-0643 Screening compound: N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)pyrazine-2-carboxamide
P073-0643 Screening compound: N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)pyrazine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P073-0643
N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)pyrazine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P073-0643

Molecular Formula

C20H17FN6O2 (C20 H17 FN6 O2)

Compound Name

N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)pyrazine-2-carboxamide

IUPAC name

N-(2-{1-[(4-fluorophenyl)methyl]-2-oxo-1H2H3H-imidazo[45-b]pyridin-3-yl}ethyl)pyrazine-2-carboxamide

SMILES

O=C(c1nccnc1)NCCN(c(nccc1)c1N1Cc(cc2)ccc2F)C1=O

InChI

InChI=1S/C20H17FN6O2/c21-15-5-3-14(4-6-15)13-27-17-2-1-7-24-18(17)26(20(27)29)11-10-25-19(28)16-12-22-8-9-23-16/h1-9,12H,10-11,13H2,(H,25,28)

InChI Key

QJRIRJYTDOWMRB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27562528

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.39

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.802

Distribution Coefficient, logD

1.802

Water Solubility, LogSw

-1.65

Polar Surface Area

71.250

Acid Dissociation Constant (pKa)

13.06

Base Dissociation Constant (pKb)

0.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

P073-0643 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Nucleic Acid Ligands (8311 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P073-0643 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P073-0643?
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What is the minimum amount of P073-0643 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P073-0643
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P073-0643
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P073-0643 available by request