P073-1050 Screening compound: N-(2-{1-[(3-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)pyrazine-2-carboxamide

P073-1050 Screening compound: N-(2-{1-[(3-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)pyrazine-2-carboxamide
P073-1050 Screening compound: N-(2-{1-[(3-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)pyrazine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P073-1050
N-(2-{1-[(3-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)pyrazine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P073-1050

Molecular Formula

C21H20N6O2 (C21 H20 N6 O2)

Compound Name

N-(2-{1-[(3-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)pyrazine-2-carboxamide

IUPAC name

N-(2-{1-[(3-methylphenyl)methyl]-2-oxo-1H2H3H-imidazo[45-b]pyridin-3-yl}ethyl)pyrazine-2-carboxamide

SMILES

Cc1cccc(CN(c2c(N3CCNC(c4nccnc4)=O)nccc2)C3=O)c1

InChI

InChI=1S/C21H20N6O2/c1-15-4-2-5-16(12-15)14-27-18-6-3-7-24-19(18)26(21(27)29)11-10-25-20(28)17-13-22-8-9-23-17/h2-9,12-13H,10-11,14H2,1H3,(H,25,28)

InChI Key

AJQDKDKCCLGEPD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27562577

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.419

Distribution Coefficient, logD

2.419

Water Solubility, LogSw

-2.38

Polar Surface Area

71.250

Acid Dissociation Constant (pKa)

13.06

Base Dissociation Constant (pKb)

0.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

P073-1050 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P073-1050 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P073-1050?
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What is the minimum amount of P073-1050 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P073-1050
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P073-1050
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P073-1050 available by request