P077-0915 Screening compound: 1-(3-chloro-2-methylphenyl)-3-[2-(thiophen-3-yl)imidazo[1,2-a]pyridin-3-yl]urea

P077-0915 Screening compound: 1-(3-chloro-2-methylphenyl)-3-[2-(thiophen-3-yl)imidazo[1,2-a]pyridin-3-yl]urea
P077-0915 Screening compound: 1-(3-chloro-2-methylphenyl)-3-[2-(thiophen-3-yl)imidazo[1,2-a]pyridin-3-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound P077-0915
1-(3-chloro-2-methylphenyl)-3-[2-(thiophen-3-yl)imidazo[1,2-a]pyridin-3-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P077-0915

Molecular Formula

C19H15ClN4OS (C19 H15 ClN4 OS)

Compound Name

1-(3-chloro-2-methylphenyl)-3-[2-(thiophen-3-yl)imidazo[1,2-a]pyridin-3-yl]urea

IUPAC name

1-(3-chloro-2-methylphenyl)-3-[2-(thiophen-3-yl)imidazo[12-a]pyridin-3-yl]urea

SMILES

Cc(c(NC(Nc1c(-c2cscc2)nc2n1cccc2)=O)ccc1)c1Cl

InChI

InChI=1S/C19H15ClN4OS/c1-12-14(20)5-4-6-15(12)21-19(25)23-18-17(13-8-10-26-11-13)22-16-7-2-3-9-24(16)18/h2-11H,1H3,(H2,21,23,25)

InChI Key

LKPGEIPNHVRAPX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27563227

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.87

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.982

Distribution Coefficient, logD

4.982

Water Solubility, LogSw

-5.06

Polar Surface Area

41.390

Acid Dissociation Constant (pKa)

11.53

Base Dissociation Constant (pKb)

-2.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

P077-0915 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Immunological Library (6760 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with P077-0915 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P077-0915?
Check Price and Availability of P077-0915, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P077-0915 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P077-0915
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P077-0915
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P077-0915 available by request