P130-0253 Screening compound: 3-cyclopentyl-1-{3-[3-(piperidin-1-yl)pyrazin-2-yl]phenyl}urea

P130-0253 Screening compound: 3-cyclopentyl-1-{3-[3-(piperidin-1-yl)pyrazin-2-yl]phenyl}urea
P130-0253 Screening compound: 3-cyclopentyl-1-{3-[3-(piperidin-1-yl)pyrazin-2-yl]phenyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound P130-0253
3-cyclopentyl-1-{3-[3-(piperidin-1-yl)pyrazin-2-yl]phenyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P130-0253

Molecular Formula

C21H27N5O (C21 H27 N5 O)

Compound Name

3-cyclopentyl-1-{3-[3-(piperidin-1-yl)pyrazin-2-yl]phenyl}urea

IUPAC name

3-cyclopentyl-1-{3-[3-(piperidin-1-yl)pyrazin-2-yl]phenyl}urea

SMILES

O=C(NC1CCCC1)Nc1cc(-c2nccnc2N2CCCCC2)ccc1

InChI

InChI=1S/C21H27N5O/c27-21(24-17-8-2-3-9-17)25-18-10-6-7-16(15-18)19-20(23-12-11-22-19)26-13-4-1-5-14-26/h6-7,10-12,15,17H,1-5,8-9,13-14H2,(H2,24,25,27)

InChI Key

BHSCRXBGDUZZTD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27566080

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.299

Distribution Coefficient, logD

4.299

Water Solubility, LogSw

-4.24

Polar Surface Area

55.935

Acid Dissociation Constant (pKa)

14.66

Base Dissociation Constant (pKb)

2.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.60

P130-0253 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P130-0253 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P130-0253?
Check Price and Availability of P130-0253, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P130-0253 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P130-0253
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P130-0253
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P130-0253 available by request