P132-0335 Screening compound: 2-{4-[4-(3-methoxyphenyl)piperazine-1-carbonyl]phenyl}-3-(pyrrolidin-1-yl)pyrazine

P132-0335 Screening compound: 2-{4-[4-(3-methoxyphenyl)piperazine-1-carbonyl]phenyl}-3-(pyrrolidin-1-yl)pyrazine
P132-0335 Screening compound: 2-{4-[4-(3-methoxyphenyl)piperazine-1-carbonyl]phenyl}-3-(pyrrolidin-1-yl)pyrazine alternative view

Chemical Structure Depiction of ChemDiv screening compound P132-0335
2-{4-[4-(3-methoxyphenyl)piperazine-1-carbonyl]phenyl}-3-(pyrrolidin-1-yl)pyrazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P132-0335

Molecular Formula

C26H29N5O2 (C26 H29 N5 O2)

Compound Name

2-{4-[4-(3-methoxyphenyl)piperazine-1-carbonyl]phenyl}-3-(pyrrolidin-1-yl)pyrazine

IUPAC name

2-{4-[4-(3-methoxyphenyl)piperazine-1-carbonyl]phenyl}-3-(pyrrolidin-1-yl)pyrazine

SMILES

COc1cccc(N(CC2)CCN2C(c(cc2)ccc2-c2nccnc2N2CCCC2)=O)c1

InChI

InChI=1S/C26H29N5O2/c1-33-23-6-4-5-22(19-23)29-15-17-31(18-16-29)26(32)21-9-7-20(8-10-21)24-25(28-12-11-27-24)30-13-2-3-14-30/h4-12,19H,2-3,13-18H2,1H3

InChI Key

RNZUZWGMVAERLW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27566262

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.55

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.512

Distribution Coefficient, logD

3.512

Water Solubility, LogSw

-3.65

Polar Surface Area

50.037

Acid Dissociation Constant (pKa)

23.50

Base Dissociation Constant (pKb)

3.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

P132-0335 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with P132-0335 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P132-0335?
Check Price and Availability of P132-0335, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P132-0335 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P132-0335
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P132-0335
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P132-0335 available by request