P132-1325 Screening compound: 4-[3-(morpholin-4-yl)pyrazin-2-yl]-N-[(2,4,6-trimethylphenyl)methyl]benzamide

P132-1325 Screening compound: 4-[3-(morpholin-4-yl)pyrazin-2-yl]-N-[(2,4,6-trimethylphenyl)methyl]benzamide
P132-1325 Screening compound: 4-[3-(morpholin-4-yl)pyrazin-2-yl]-N-[(2,4,6-trimethylphenyl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P132-1325
4-[3-(morpholin-4-yl)pyrazin-2-yl]-N-[(2,4,6-trimethylphenyl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P132-1325

Molecular Formula

C25H28N4O2 (C25 H28 N4 O2)

Compound Name

4-[3-(morpholin-4-yl)pyrazin-2-yl]-N-[(2,4,6-trimethylphenyl)methyl]benzamide

IUPAC name

4-[3-(morpholin-4-yl)pyrazin-2-yl]-N-[(246-trimethylphenyl)methyl]benzamide

SMILES

Cc1cc(C)c(CNC(c(cc2)ccc2-c2nccnc2N2CCOCC2)=O)c(C)c1

InChI

InChI=1S/C25H28N4O2/c1-17-14-18(2)22(19(3)15-17)16-28-25(30)21-6-4-20(5-7-21)23-24(27-9-8-26-23)29-10-12-31-13-11-29/h4-9,14-15H,10-13,16H2,1-3H3,(H,28,30)

InChI Key

JELPRXJKCXBRCM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27566378

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.404

Distribution Coefficient, logD

4.404

Water Solubility, LogSw

-4.26

Polar Surface Area

54.540

Acid Dissociation Constant (pKa)

10.37

Base Dissociation Constant (pKb)

2.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

P132-1325 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with P132-1325 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P132-1325?
Check Price and Availability of P132-1325, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P132-1325 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P132-1325
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P132-1325
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P132-1325 available by request