P147-0744 Screening compound: N-({1-[4-(3-methylpiperidine-1-carbonyl)phenyl]-1H-pyrazol-4-yl}methyl)cyclopropanecarboxamide

P147-0744 Screening compound: N-({1-[4-(3-methylpiperidine-1-carbonyl)phenyl]-1H-pyrazol-4-yl}methyl)cyclopropanecarboxamide
P147-0744 Screening compound: N-({1-[4-(3-methylpiperidine-1-carbonyl)phenyl]-1H-pyrazol-4-yl}methyl)cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P147-0744
N-({1-[4-(3-methylpiperidine-1-carbonyl)phenyl]-1H-pyrazol-4-yl}methyl)cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P147-0744

Molecular Formula

C21H26N4O2 (C21 H26 N4 O2)

Compound Name

N-({1-[4-(3-methylpiperidine-1-carbonyl)phenyl]-1H-pyrazol-4-yl}methyl)cyclopropanecarboxamide

IUPAC name

N-({1-[4-(3-methylpiperidine-1-carbonyl)phenyl]-1H-pyrazol-4-yl}methyl)cyclopropanecarboxamide

SMILES

CC(CCC1)CN1C(c(cc1)ccc1-n1ncc(CNC(C2CC2)=O)c1)=O

InChI

InChI=1S/C21H26N4O2/c1-15-3-2-10-24(13-15)21(27)18-6-8-19(9-7-18)25-14-16(12-23-25)11-22-20(26)17-4-5-17/h6-9,12,14-15,17H,2-5,10-11,13H2,1H3,(H,22,26)/t15-/m0/s1

InChI Key

RUJGWZRJJUWKAZ-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD29020179

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.048

Distribution Coefficient, logD

2.048

Water Solubility, LogSw

-2.60

Polar Surface Area

56.114

Acid Dissociation Constant (pKa)

14.50

Base Dissociation Constant (pKb)

7.74

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

47.60

P147-0744 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P147-0744 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P147-0744?
Check Price and Availability of P147-0744, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P147-0744 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P147-0744
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P147-0744
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P147-0744 available by request