P150-0901 Screening compound: 1H-imidazol-4-yl [2-(4-methylpiperazino)-6,7-dihydro[1,3]thiazolo[5,4-c]pyridin-5(4H)-yl] sulfone

P150-0901 Screening compound: 1H-imidazol-4-yl [2-(4-methylpiperazino)-6,7-dihydro[1,3]thiazolo[5,4-c]pyridin-5(4H)-yl] sulfone
P150-0901 Screening compound: 1H-imidazol-4-yl [2-(4-methylpiperazino)-6,7-dihydro[1,3]thiazolo[5,4-c]pyridin-5(4H)-yl] sulfone alternative view

Chemical Structure Depiction of ChemDiv screening compound P150-0901
1H-imidazol-4-yl [2-(4-methylpiperazino)-6,7-dihydro[1,3]thiazolo[5,4-c]pyridin-5(4H)-yl] sulfone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P150-0901

Molecular Formula

C14H20N6O2S2 (C14 H20 N6 O2 S2)

Compound Name

1H-imidazol-4-yl [2-(4-methylpiperazino)-6,7-dihydro[1,3]thiazolo[5,4-c]pyridin-5(4H)-yl] sulfone

IUPAC name

1-[5-(1H-imidazole-4-sulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]-4-methylpiperazine

SMILES

CN(CC1)CCN1c1nc(CCN(C2)S(c3c[nH]cn3)(=O)=O)c2s1

InChI

InChI=1S/C14H20N6O2S2/c1-18-4-6-19(7-5-18)14-17-11-2-3-20(9-12(11)23-14)24(21,22)13-8-15-10-16-13/h8,10H,2-7,9H2,1H3,(H,15,16)

InChI Key

WVFVWZHRQGWHGV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28996216

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.843

Distribution Coefficient, logD

0.119

Water Solubility, LogSw

-2.07

Polar Surface Area

70.935

Acid Dissociation Constant (pKa)

9.20

Base Dissociation Constant (pKb)

8.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.14

P150-0901 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Bromodomain Modulators Library (5801 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Mechanism of action:
  • PPI modulators
  • Epigenetic
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds
Targets:
  • Others

References: we are preparing a list of scientific research reports with P150-0901 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P150-0901?
Check Price and Availability of P150-0901, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P150-0901 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P150-0901
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P150-0901
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P150-0901 available by request