P150-1136 Screening compound: 2-(4-ethylpiperazin-1-yl)-N-propyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-5-carboxamide

P150-1136 Screening compound: 2-(4-ethylpiperazin-1-yl)-N-propyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-5-carboxamide
P150-1136 Screening compound: 2-(4-ethylpiperazin-1-yl)-N-propyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P150-1136
2-(4-ethylpiperazin-1-yl)-N-propyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P150-1136

Molecular Formula

C16H27N5OS (C16 H27 N5 OS)

Compound Name

2-(4-ethylpiperazin-1-yl)-N-propyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-5-carboxamide

IUPAC name

2-(4-ethylpiperazin-1-yl)-N-propyl-4H5H6H7H-[13]thiazolo[54-c]pyridine-5-carboxamide

SMILES

CCCNC(N(CC1)Cc2c1nc(N1CCN(CC)CC1)s2)=O

InChI

InChI=1S/C16H27N5OS/c1-3-6-17-15(22)21-7-5-13-14(12-21)23-16(18-13)20-10-8-19(4-2)9-11-20/h3-12H2,1-2H3,(H,17,22)

InChI Key

BQTQGZKNGWDVHV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28996202

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

337.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.282

Distribution Coefficient, logD

1.429

Water Solubility, LogSw

-2.39

Polar Surface Area

45.115

Acid Dissociation Constant (pKa)

16.95

Base Dissociation Constant (pKb)

8.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

75.00

P150-1136 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with P150-1136 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P150-1136?
Check Price and Availability of P150-1136, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P150-1136 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P150-1136
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P150-1136
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P150-1136 available by request