P163-0377 Screening compound: ethyl 4-{4-ethyl-7-hydroxy-5-oxo-4H,5H-thieno[3,2-b]pyridine-6-amido}benzoate

P163-0377 Screening compound: ethyl 4-{4-ethyl-7-hydroxy-5-oxo-4H,5H-thieno[3,2-b]pyridine-6-amido}benzoate
P163-0377 Screening compound: ethyl 4-{4-ethyl-7-hydroxy-5-oxo-4H,5H-thieno[3,2-b]pyridine-6-amido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound P163-0377
ethyl 4-{4-ethyl-7-hydroxy-5-oxo-4H,5H-thieno[3,2-b]pyridine-6-amido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P163-0377

Molecular Formula

C19H18N2O5S (C19 H18 N2 O5 S)

Compound Name

ethyl 4-{4-ethyl-7-hydroxy-5-oxo-4H,5H-thieno[3,2-b]pyridine-6-amido}benzoate

IUPAC name

ethyl 4-{4-ethyl-7-hydroxy-5-oxo-4H5H-thieno[32-b]pyridine-6-amido}benzoate

SMILES

CCN(c1c(C(O)=C2C(Nc(cc3)ccc3C(OCC)=O)=O)scc1)C2=O

InChI

InChI=1S/C19H18N2O5S/c1-3-21-13-9-10-27-16(13)15(22)14(18(21)24)17(23)20-12-7-5-11(6-8-12)19(25)26-4-2/h5-10,22H,3-4H2,1-2H3,(H,20,23)

InChI Key

OSICLFZYTHQBFH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29020453

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.43

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.073

Distribution Coefficient, logD

-3.082

Water Solubility, LogSw

-3.44

Polar Surface Area

75.272

Acid Dissociation Constant (pKa)

1.24

Base Dissociation Constant (pKb)

-1.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

P163-0377 in Drug Discovery

Included in Screening Libraries

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with P163-0377 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P163-0377?
Check Price and Availability of P163-0377, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P163-0377 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P163-0377
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P163-0377
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P163-0377 available by request