P163-0851 Screening compound: 2-(4-{4-benzyl-7-hydroxy-5-oxo-4H,5H-thieno[3,2-b]pyridine-6-amido}phenyl)acetic acid

P163-0851 Screening compound: 2-(4-{4-benzyl-7-hydroxy-5-oxo-4H,5H-thieno[3,2-b]pyridine-6-amido}phenyl)acetic acid
P163-0851 Screening compound: 2-(4-{4-benzyl-7-hydroxy-5-oxo-4H,5H-thieno[3,2-b]pyridine-6-amido}phenyl)acetic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound P163-0851
2-(4-{4-benzyl-7-hydroxy-5-oxo-4H,5H-thieno[3,2-b]pyridine-6-amido}phenyl)acetic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P163-0851

Molecular Formula

C23H18N2O5S (C23 H18 N2 O5 S)

Compound Name

2-(4-{4-benzyl-7-hydroxy-5-oxo-4H,5H-thieno[3,2-b]pyridine-6-amido}phenyl)acetic acid

IUPAC name

2-(4-{4-benzyl-7-hydroxy-5-oxo-4H5H-thieno[32-b]pyridine-6-amido}phenyl)acetic acid

SMILES

OC(Cc(cc1)ccc1NC(C(C(N(Cc1ccccc1)c1c2scc1)=O)=C2O)=O)=O

InChI

InChI=1S/C23H18N2O5S/c26-18(27)12-14-6-8-16(9-7-14)24-22(29)19-20(28)21-17(10-11-31-21)25(23(19)30)13-15-4-2-1-3-5-15/h1-11,28H,12-13H2,(H,24,29)(H,26,27)

InChI Key

UHVJBWZEPBBRQH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD20754968

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.052

Distribution Coefficient, logD

-3.452

Water Solubility, LogSw

-3.49

Polar Surface Area

82.906

Acid Dissociation Constant (pKa)

0.90

Base Dissociation Constant (pKb)

0.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

P163-0851 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with P163-0851 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P163-0851?
Check Price and Availability of P163-0851, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P163-0851 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P163-0851
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P163-0851
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P163-0851 available by request