P165-2786 Screening compound: ethyl 4-{2-[3-(hydroxymethyl)-4-oxo-2-phenyl-4H,5H-pyrazolo[1,5-a]pyrazin-5-yl]acetamido}benzoate

P165-2786 Screening compound: ethyl 4-{2-[3-(hydroxymethyl)-4-oxo-2-phenyl-4H,5H-pyrazolo[1,5-a]pyrazin-5-yl]acetamido}benzoate
P165-2786 Screening compound: ethyl 4-{2-[3-(hydroxymethyl)-4-oxo-2-phenyl-4H,5H-pyrazolo[1,5-a]pyrazin-5-yl]acetamido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound P165-2786
ethyl 4-{2-[3-(hydroxymethyl)-4-oxo-2-phenyl-4H,5H-pyrazolo[1,5-a]pyrazin-5-yl]acetamido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P165-2786

Molecular Formula

C24H22N4O5 (C24 H22 N4 O5)

Compound Name

ethyl 4-{2-[3-(hydroxymethyl)-4-oxo-2-phenyl-4H,5H-pyrazolo[1,5-a]pyrazin-5-yl]acetamido}benzoate

IUPAC name

ethyl 4-{2-[3-(hydroxymethyl)-4-oxo-2-phenyl-4H5H-pyrazolo[15-a]pyrazin-5-yl]acetamido}benzoate

SMILES

CCOC(c(cc1)ccc1NC(CN(C=Cn(c1c2CO)nc2-c2ccccc2)C1=O)=O)=O

InChI

InChI=1S/C24H22N4O5/c1-2-33-24(32)17-8-10-18(11-9-17)25-20(30)14-27-12-13-28-22(23(27)31)19(15-29)21(26-28)16-6-4-3-5-7-16/h3-13,29H,2,14-15H2,1H3,(H,25,30)

InChI Key

RTOKZPDCBMZZOL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28996631

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.46

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.856

Distribution Coefficient, logD

1.856

Water Solubility, LogSw

-2.30

Polar Surface Area

89.535

Acid Dissociation Constant (pKa)

11.13

Base Dissociation Constant (pKb)

-1.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

P165-2786 in Drug Discovery

Included in Screening Libraries

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P165-2786 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P165-2786?
Check Price and Availability of P165-2786, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P165-2786 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P165-2786
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P165-2786
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P165-2786 available by request