P169-1228 Screening compound: 2,5-dimethyl-N-({2-methyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)benzene-1-sulfonamide

P169-1228 Screening compound: 2,5-dimethyl-N-({2-methyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)benzene-1-sulfonamide
P169-1228 Screening compound: 2,5-dimethyl-N-({2-methyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P169-1228
2,5-dimethyl-N-({2-methyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P169-1228

Molecular Formula

C20H20N4O2S2 (C20 H20 N4 O2 S2)

Compound Name

2,5-dimethyl-N-({2-methyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)benzene-1-sulfonamide

IUPAC name

25-dimethyl-N-({2-methyl-6-phenylimidazo[21-b][134]thiadiazol-5-yl}methyl)benzene-1-sulfonamide

SMILES

Cc(s1)nn2c1nc(-c1ccccc1)c2CNS(c1c(C)ccc(C)c1)(=O)=O

InChI

InChI=1S/C20H20N4O2S2/c1-13-9-10-14(2)18(11-13)28(25,26)21-12-17-19(16-7-5-4-6-8-16)22-20-24(17)23-15(3)27-20/h4-11,21H,12H2,1-3H3

InChI Key

PARAZFMLBSUGBY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27567736

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.916

Distribution Coefficient, logD

3.847

Water Solubility, LogSw

-3.86

Polar Surface Area

62.586

Acid Dissociation Constant (pKa)

8.17

Base Dissociation Constant (pKb)

2.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

P169-1228 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
Agro:
  • Agro
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P169-1228 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P169-1228?
Check Price and Availability of P169-1228, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P169-1228 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P169-1228
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P169-1228
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P169-1228 available by request