P169-2130 Screening compound: N-({2-methyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)benzamide

P169-2130 Screening compound: N-({2-methyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)benzamide
P169-2130 Screening compound: N-({2-methyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P169-2130
N-({2-methyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P169-2130

Molecular Formula

C19H16N4OS (C19 H16 N4 OS)

Compound Name

N-({2-methyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)benzamide

IUPAC name

N-({2-methyl-6-phenylimidazo[21-b][134]thiadiazol-5-yl}methyl)benzamide

SMILES

Cc(s1)nn2c1nc(-c1ccccc1)c2CNC(c1ccccc1)=O

InChI

InChI=1S/C19H16N4OS/c1-13-22-23-16(12-20-18(24)15-10-6-3-7-11-15)17(21-19(23)25-13)14-8-4-2-5-9-14/h2-11H,12H2,1H3,(H,20,24)

InChI Key

DJYBEUMWQUVWDF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27567920

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

348.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.032

Distribution Coefficient, logD

3.031

Water Solubility, LogSw

-3.27

Polar Surface Area

45.241

Acid Dissociation Constant (pKa)

11.16

Base Dissociation Constant (pKb)

-0.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

P169-2130 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P169-2130 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P169-2130?
Check Price and Availability of P169-2130, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P169-2130 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P169-2130
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P169-2130
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P169-2130 available by request