P169-2268 Screening compound: N-({2-ethyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)-3,5-dimethylbenzamide

P169-2268 Screening compound: N-({2-ethyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)-3,5-dimethylbenzamide
P169-2268 Screening compound: N-({2-ethyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)-3,5-dimethylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P169-2268
N-({2-ethyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)-3,5-dimethylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P169-2268

Molecular Formula

C22H22N4OS (C22 H22 N4 OS)

Compound Name

N-({2-ethyl-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl}methyl)-3,5-dimethylbenzamide

IUPAC name

N-({2-ethyl-6-phenylimidazo[21-b][134]thiadiazol-5-yl}methyl)-35-dimethylbenzamide

SMILES

CCc(s1)nn2c1nc(-c1ccccc1)c2CNC(c1cc(C)cc(C)c1)=O

InChI

InChI=1S/C22H22N4OS/c1-4-19-25-26-18(13-23-21(27)17-11-14(2)10-15(3)12-17)20(24-22(26)28-19)16-8-6-5-7-9-16/h5-12H,4,13H2,1-3H3,(H,23,27)

InChI Key

UFSXVOOIYPDEEB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27567928

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.756

Distribution Coefficient, logD

4.755

Water Solubility, LogSw

-4.49

Polar Surface Area

45.930

Acid Dissociation Constant (pKa)

10.08

Base Dissociation Constant (pKb)

0.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

P169-2268 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

PLpro Library (6343 compounds)

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P169-2268 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P169-2268?
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What is the minimum amount of P169-2268 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P169-2268
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P169-2268
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P169-2268 available by request