P177-0081 Screening compound: N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]pyridine-2-carboxamide

P177-0081 Screening compound: N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]pyridine-2-carboxamide
P177-0081 Screening compound: N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]pyridine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P177-0081
N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]pyridine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P177-0081

Molecular Formula

C14H12N4OS (C14 H12 N4 OS)

Compound Name

N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]pyridine-2-carboxamide

IUPAC name

N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]pyridine-2-carboxamide

SMILES

Cc(sc(-c1ccn[nH]1)c1)c1NC(c1ncccc1)=O

InChI

InChI=1S/C14H12N4OS/c1-9-12(8-13(20-9)10-5-7-16-18-10)17-14(19)11-4-2-3-6-15-11/h2-8H,1H3,(H,16,18)(H,17,19)

InChI Key

XDLSEOZWBYPOAO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27568069

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

284.34

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.546

Distribution Coefficient, logD

2.544

Water Solubility, LogSw

-2.99

Polar Surface Area

56.028

Acid Dissociation Constant (pKa)

12.20

Base Dissociation Constant (pKb)

5.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.10

P177-0081 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Fragments Library (11262 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Structure:
  • Fragments
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P177-0081 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P177-0081?
Check Price and Availability of P177-0081, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P177-0081 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P177-0081
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P177-0081
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P177-0081 available by request