P177-0114 Screening compound: 2-(2-fluorophenyl)-N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]acetamide

P177-0114 Screening compound: 2-(2-fluorophenyl)-N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]acetamide
P177-0114 Screening compound: 2-(2-fluorophenyl)-N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P177-0114
2-(2-fluorophenyl)-N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P177-0114

Molecular Formula

C16H14FN3OS (C16 H14 FN3 OS)

Compound Name

2-(2-fluorophenyl)-N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]acetamide

IUPAC name

2-(2-fluorophenyl)-N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]acetamide

SMILES

Cc(sc(-c1ccn[nH]1)c1)c1NC(Cc(cccc1)c1F)=O

InChI

InChI=1S/C16H14FN3OS/c1-10-14(9-15(22-10)13-6-7-18-20-13)19-16(21)8-11-4-2-3-5-12(11)17/h2-7,9H,8H2,1H3,(H,18,20)(H,19,21)

InChI Key

HFEDHUJSRMYJPB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27568075

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

315.37

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.488

Distribution Coefficient, logD

3.486

Water Solubility, LogSw

-3.78

Polar Surface Area

46.767

Acid Dissociation Constant (pKa)

10.89

Base Dissociation Constant (pKb)

5.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

P177-0114 in Drug Discovery

Included in Screening Libraries

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P177-0114 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P177-0114?
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What is the minimum amount of P177-0114 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P177-0114
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P177-0114
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P177-0114 available by request