P177-0144 Screening compound: 3-cyano-N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]benzamide

P177-0144 Screening compound: 3-cyano-N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]benzamide
P177-0144 Screening compound: 3-cyano-N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P177-0144
3-cyano-N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P177-0144

Molecular Formula

C16H12N4OS (C16 H12 N4 OS)

Compound Name

3-cyano-N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]benzamide

IUPAC name

3-cyano-N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]benzamide

SMILES

Cc(sc(-c1ccn[nH]1)c1)c1NC(c1cc(C#N)ccc1)=O

InChI

InChI=1S/C16H12N4OS/c1-10-14(8-15(22-10)13-5-6-18-20-13)19-16(21)12-4-2-3-11(7-12)9-17/h2-8H,1H3,(H,18,20)(H,19,21)

InChI Key

NZMAJCKZSSTRDB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27568081

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

308.36

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.039

Distribution Coefficient, logD

3.037

Water Solubility, LogSw

-3.41

Polar Surface Area

64.036

Acid Dissociation Constant (pKa)

11.22

Base Dissociation Constant (pKb)

5.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.30

P177-0144 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with P177-0144 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P177-0144?
Check Price and Availability of P177-0144, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P177-0144 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P177-0144
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P177-0144
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P177-0144 available by request