P177-0147 Screening compound: N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]quinoline-2-carboxamide

P177-0147 Screening compound: N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]quinoline-2-carboxamide
P177-0147 Screening compound: N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]quinoline-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P177-0147
N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]quinoline-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P177-0147

Molecular Formula

C18H14N4OS (C18 H14 N4 OS)

Compound Name

N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]quinoline-2-carboxamide

IUPAC name

N-[2-methyl-5-(1H-pyrazol-5-yl)thiophen-3-yl]quinoline-2-carboxamide

SMILES

Cc(sc(-c1ccn[nH]1)c1)c1NC(c1nc2ccccc2cc1)=O

InChI

InChI=1S/C18H14N4OS/c1-11-16(10-17(24-11)14-8-9-19-22-14)21-18(23)15-7-6-12-4-2-3-5-13(12)20-15/h2-10H,1H3,(H,19,22)(H,21,23)

InChI Key

OTONHGGJNQUIEF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27568082

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

334.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.958

Distribution Coefficient, logD

3.956

Water Solubility, LogSw

-3.95

Polar Surface Area

55.311

Acid Dissociation Constant (pKa)

12.33

Base Dissociation Constant (pKb)

5.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

P177-0147 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Nervous system
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P177-0147 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P177-0147?
Check Price and Availability of P177-0147, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P177-0147 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P177-0147
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P177-0147
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P177-0147 available by request