P180-0521 Screening compound: N-[2-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)thiophen-3-yl]-1H-indazole-3-carboxamide

P180-0521 Screening compound: N-[2-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)thiophen-3-yl]-1H-indazole-3-carboxamide
P180-0521 Screening compound: N-[2-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)thiophen-3-yl]-1H-indazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P180-0521
N-[2-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)thiophen-3-yl]-1H-indazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P180-0521

Molecular Formula

C17H13N5O2S (C17 H13 N5 O2 S)

Compound Name

N-[2-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)thiophen-3-yl]-1H-indazole-3-carboxamide

IUPAC name

N-[2-(5-cyclopropyl-134-oxadiazol-2-yl)thiophen-3-yl]-1H-indazole-3-carboxamide

SMILES

O=C(c1n[nH]c2c1cccc2)Nc1c(-c2nnc(C3CC3)o2)scc1

InChI

InChI=1S/C17H13N5O2S/c23-15(13-10-3-1-2-4-11(10)19-20-13)18-12-7-8-25-14(12)17-22-21-16(24-17)9-5-6-9/h1-4,7-9H,5-6H2,(H,18,23)(H,19,20)

InChI Key

MDRFOVOUVIHNHN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27568133

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.256

Distribution Coefficient, logD

3.256

Water Solubility, LogSw

-3.47

Polar Surface Area

77.664

Acid Dissociation Constant (pKa)

15.05

Base Dissociation Constant (pKb)

0.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.60

P180-0521 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Angiogenesis library (14822 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with P180-0521 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P180-0521?
Check Price and Availability of P180-0521, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P180-0521 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P180-0521
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P180-0521
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P180-0521 available by request