P180-1026 Screening compound: N-{2-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]thiophen-3-yl}quinoline-2-carboxamide

P180-1026 Screening compound: N-{2-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]thiophen-3-yl}quinoline-2-carboxamide
P180-1026 Screening compound: N-{2-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]thiophen-3-yl}quinoline-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P180-1026
N-{2-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]thiophen-3-yl}quinoline-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P180-1026

Molecular Formula

C19H16N4O2S (C19 H16 N4 O2 S)

Compound Name

N-{2-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]thiophen-3-yl}quinoline-2-carboxamide

IUPAC name

N-{2-[5-(propan-2-yl)-134-oxadiazol-2-yl]thiophen-3-yl}quinoline-2-carboxamide

SMILES

CC(C)c1nnc(-c(scc2)c2NC(c2nc3ccccc3cc2)=O)o1

InChI

InChI=1S/C19H16N4O2S/c1-11(2)18-22-23-19(25-18)16-14(9-10-26-16)21-17(24)15-8-7-12-5-3-4-6-13(12)20-15/h3-11H,1-2H3,(H,21,24)

InChI Key

IZJXPSAOIZQFSR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27568180

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.024

Distribution Coefficient, logD

4.024

Water Solubility, LogSw

-4.30

Polar Surface Area

62.497

Acid Dissociation Constant (pKa)

12.32

Base Dissociation Constant (pKb)

0.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

P180-1026 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with P180-1026 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P180-1026?
Check Price and Availability of P180-1026, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P180-1026 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P180-1026
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P180-1026
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P180-1026 available by request