P181-1288 Screening compound: 3-bromo-N-{2-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]thiophen-3-yl}benzamide

P181-1288 Screening compound: 3-bromo-N-{2-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]thiophen-3-yl}benzamide
P181-1288 Screening compound: 3-bromo-N-{2-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]thiophen-3-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P181-1288
3-bromo-N-{2-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]thiophen-3-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P181-1288

Molecular Formula

C19H11BrFN3O2S (C19 H11 BrFN3 O2 S)

Compound Name

3-bromo-N-{2-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]thiophen-3-yl}benzamide

IUPAC name

3-bromo-N-{2-[3-(3-fluorophenyl)-124-oxadiazol-5-yl]thiophen-3-yl}benzamide

SMILES

O=C(c1cccc(Br)c1)Nc1c(-c2nc(-c3cc(F)ccc3)no2)scc1

InChI

InChI=1S/C19H11BrFN3O2S/c20-13-5-1-4-12(9-13)18(25)22-15-7-8-27-16(15)19-23-17(24-26-19)11-3-2-6-14(21)10-11/h1-10H,(H,22,25)

InChI Key

CLXCZOPZNVUXOO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27568454

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.28

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.789

Distribution Coefficient, logD

5.788

Water Solubility, LogSw

-5.96

Polar Surface Area

55.056

Acid Dissociation Constant (pKa)

10.79

Base Dissociation Constant (pKb)

-5.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

P181-1288 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with P181-1288 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P181-1288?
Check Price and Availability of P181-1288, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P181-1288 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P181-1288
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P181-1288
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P181-1288 available by request