P184-1427 Screening compound: N-[(1-benzyl-1H-indazol-3-yl)methyl]-2,4-dimethyl-1,3-thiazole-5-carboxamide

P184-1427 Screening compound: N-[(1-benzyl-1H-indazol-3-yl)methyl]-2,4-dimethyl-1,3-thiazole-5-carboxamide
P184-1427 Screening compound: N-[(1-benzyl-1H-indazol-3-yl)methyl]-2,4-dimethyl-1,3-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P184-1427
N-[(1-benzyl-1H-indazol-3-yl)methyl]-2,4-dimethyl-1,3-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P184-1427

Molecular Formula

C21H20N4OS (C21 H20 N4 OS)

Compound Name

N-[(1-benzyl-1H-indazol-3-yl)methyl]-2,4-dimethyl-1,3-thiazole-5-carboxamide

IUPAC name

N-[(1-benzyl-1H-indazol-3-yl)methyl]-24-dimethyl-13-thiazole-5-carboxamide

SMILES

Cc1c(C(NCc2nn(Cc3ccccc3)c3c2cccc3)=O)sc(C)n1

InChI

InChI=1S/C21H20N4OS/c1-14-20(27-15(2)23-14)21(26)22-12-18-17-10-6-7-11-19(17)25(24-18)13-16-8-4-3-5-9-16/h3-11H,12-13H2,1-2H3,(H,22,26)

InChI Key

MUXHTAOCHBEPJT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27568732

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.770

Distribution Coefficient, logD

3.770

Water Solubility, LogSw

-4.00

Polar Surface Area

49.514

Acid Dissociation Constant (pKa)

11.26

Base Dissociation Constant (pKb)

2.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

P184-1427 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

GPCR Targeted Library (31838 compounds)

Antibacterial Compounds Library (13827 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Immune system
  • animal
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P184-1427 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P184-1427?
Check Price and Availability of P184-1427, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P184-1427 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P184-1427
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P184-1427
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P184-1427 available by request