P188-1460 Screening compound: 2-{1-[(3-fluorophenyl)methyl]-7-oxo-1H,6H,7H-pyrrolo[2,3-c]pyridin-6-yl}-N-[(3-methoxyphenyl)methyl]acetamide

P188-1460 Screening compound: 2-{1-[(3-fluorophenyl)methyl]-7-oxo-1H,6H,7H-pyrrolo[2,3-c]pyridin-6-yl}-N-[(3-methoxyphenyl)methyl]acetamide
P188-1460 Screening compound: 2-{1-[(3-fluorophenyl)methyl]-7-oxo-1H,6H,7H-pyrrolo[2,3-c]pyridin-6-yl}-N-[(3-methoxyphenyl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P188-1460
2-{1-[(3-fluorophenyl)methyl]-7-oxo-1H,6H,7H-pyrrolo[2,3-c]pyridin-6-yl}-N-[(3-methoxyphenyl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P188-1460

Molecular Formula

C24H22FN3O3 (C24 H22 FN3 O3)

Compound Name

2-{1-[(3-fluorophenyl)methyl]-7-oxo-1H,6H,7H-pyrrolo[2,3-c]pyridin-6-yl}-N-[(3-methoxyphenyl)methyl]acetamide

IUPAC name

2-{1-[(3-fluorophenyl)methyl]-7-oxo-1H6H7H-pyrrolo[23-c]pyridin-6-yl}-N-[(3-methoxyphenyl)methyl]acetamide

SMILES

COc1cccc(CNC(CN(C=Cc2c3n(Cc4cccc(F)c4)cc2)C3=O)=O)c1

InChI

InChI=1S/C24H22FN3O3/c1-31-21-7-3-4-17(13-21)14-26-22(29)16-28-11-9-19-8-10-27(23(19)24(28)30)15-18-5-2-6-20(25)12-18/h2-13H,14-16H2,1H3,(H,26,29)

InChI Key

RKMYYGSSGNNIFM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27568943

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.793

Distribution Coefficient, logD

2.793

Water Solubility, LogSw

-3.29

Polar Surface Area

49.673

Acid Dissociation Constant (pKa)

13.90

Base Dissociation Constant (pKb)

-0.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

P188-1460 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with P188-1460 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P188-1460?
Check Price and Availability of P188-1460, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P188-1460 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P188-1460
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P188-1460
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P188-1460 available by request