P194-1238 Screening compound: N-(3-chloro-4-methylphenyl)-2-[4-methyl-6-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide

P194-1238 Screening compound: N-(3-chloro-4-methylphenyl)-2-[4-methyl-6-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide
P194-1238 Screening compound: N-(3-chloro-4-methylphenyl)-2-[4-methyl-6-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P194-1238
N-(3-chloro-4-methylphenyl)-2-[4-methyl-6-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P194-1238

Molecular Formula

C23H23ClN4O2 (C23 H23 ClN4 O2)

Compound Name

N-(3-chloro-4-methylphenyl)-2-[4-methyl-6-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1,6-dihydropyrimidin-1-yl]acetamide

IUPAC name

N-(3-chloro-4-methylphenyl)-2-[4-methyl-6-oxo-2-(1234-tetrahydroisoquinolin-2-yl)-16-dihydropyrimidin-1-yl]acetamide

SMILES

Cc(ccc(NC(CN1C(N(CC2)Cc3c2cccc3)=NC(C)=CC1=O)=O)c1)c1Cl

InChI

InChI=1S/C23H23ClN4O2/c1-15-7-8-19(12-20(15)24)26-21(29)14-28-22(30)11-16(2)25-23(28)27-10-9-17-5-3-4-6-18(17)13-27/h3-8,11-12H,9-10,13-14H2,1-2H3,(H,26,29)

InChI Key

BFVIQOFWEYAYBA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28994895

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.91

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.395

Distribution Coefficient, logD

4.394

Water Solubility, LogSw

-4.44

Polar Surface Area

51.767

Acid Dissociation Constant (pKa)

10.95

Base Dissociation Constant (pKb)

1.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

P194-1238 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with P194-1238 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P194-1238?
Check Price and Availability of P194-1238, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P194-1238 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P194-1238
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P194-1238
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P194-1238 available by request