P194-1275 Screening compound: 2-[4-methyl-6-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1,6-dihydropyrimidin-1-yl]-N-phenylacetamide

P194-1275 Screening compound: 2-[4-methyl-6-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1,6-dihydropyrimidin-1-yl]-N-phenylacetamide
P194-1275 Screening compound: 2-[4-methyl-6-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1,6-dihydropyrimidin-1-yl]-N-phenylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P194-1275
2-[4-methyl-6-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1,6-dihydropyrimidin-1-yl]-N-phenylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P194-1275

Molecular Formula

C22H22N4O2 (C22 H22 N4 O2)

Compound Name

2-[4-methyl-6-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1,6-dihydropyrimidin-1-yl]-N-phenylacetamide

IUPAC name

2-[4-methyl-6-oxo-2-(1234-tetrahydroisoquinolin-2-yl)-16-dihydropyrimidin-1-yl]-N-phenylacetamide

SMILES

CC(N=C(N1CC(Nc2ccccc2)=O)N(CC2)Cc3c2cccc3)=CC1=O

InChI

InChI=1S/C22H22N4O2/c1-16-13-21(28)26(15-20(27)24-19-9-3-2-4-10-19)22(23-16)25-12-11-17-7-5-6-8-18(17)14-25/h2-10,13H,11-12,14-15H2,1H3,(H,24,27)

InChI Key

IMTNMXUPZADPPF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD18200876

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.813

Distribution Coefficient, logD

2.813

Water Solubility, LogSw

-3.22

Polar Surface Area

51.767

Acid Dissociation Constant (pKa)

12.95

Base Dissociation Constant (pKb)

1.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

P194-1275 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with P194-1275 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P194-1275?
Check Price and Availability of P194-1275, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P194-1275 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P194-1275
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P194-1275
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P194-1275 available by request