P194-1447 Screening compound: N-(2,5-difluorophenyl)-2-[4-(methoxymethyl)-2-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-1-yl]acetamide

P194-1447 Screening compound: N-(2,5-difluorophenyl)-2-[4-(methoxymethyl)-2-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-1-yl]acetamide
P194-1447 Screening compound: N-(2,5-difluorophenyl)-2-[4-(methoxymethyl)-2-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P194-1447
N-(2,5-difluorophenyl)-2-[4-(methoxymethyl)-2-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P194-1447

Molecular Formula

C18H20F2N4O4 (C18 H20 F2 N4 O4)

Compound Name

N-(2,5-difluorophenyl)-2-[4-(methoxymethyl)-2-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-1-yl]acetamide

IUPAC name

N-(25-difluorophenyl)-2-[4-(methoxymethyl)-2-(morpholin-4-yl)-6-oxo-16-dihydropyrimidin-1-yl]acetamide

SMILES

COCC(N=C(N1CC(Nc(cc(cc2)F)c2F)=O)N2CCOCC2)=CC1=O

InChI

InChI=1S/C18H20F2N4O4/c1-27-11-13-9-17(26)24(18(21-13)23-4-6-28-7-5-23)10-16(25)22-15-8-12(19)2-3-14(15)20/h2-3,8-9H,4-7,10-11H2,1H3,(H,22,25)

InChI Key

WMCALXNPSPFZIE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD18786905

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.38

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.935

Distribution Coefficient, logD

0.928

Water Solubility, LogSw

-2.15

Polar Surface Area

68.347

Acid Dissociation Constant (pKa)

9.19

Base Dissociation Constant (pKb)

-0.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

P194-1447 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

PI3K-Targeted Library (17255 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with P194-1447 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P194-1447?
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What is the minimum amount of P194-1447 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P194-1447
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P194-1447
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P194-1447 available by request