P194-1564 Screening compound: N-(4-bromo-2-fluorophenyl)-2-[4-methyl-6-oxo-2-(4-phenylpiperazin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide

P194-1564 Screening compound: N-(4-bromo-2-fluorophenyl)-2-[4-methyl-6-oxo-2-(4-phenylpiperazin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide
P194-1564 Screening compound: N-(4-bromo-2-fluorophenyl)-2-[4-methyl-6-oxo-2-(4-phenylpiperazin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P194-1564
N-(4-bromo-2-fluorophenyl)-2-[4-methyl-6-oxo-2-(4-phenylpiperazin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P194-1564

Molecular Formula

C23H23BrFN5O2 (C23 H23 BrFN5 O2)

Compound Name

N-(4-bromo-2-fluorophenyl)-2-[4-methyl-6-oxo-2-(4-phenylpiperazin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide

IUPAC name

N-(4-bromo-2-fluorophenyl)-2-[4-methyl-6-oxo-2-(4-phenylpiperazin-1-yl)-16-dihydropyrimidin-1-yl]acetamide

SMILES

CC(N=C(N1CC(Nc(ccc(Br)c2)c2F)=O)N(CC2)CCN2c2ccccc2)=CC1=O

InChI

InChI=1S/C23H23BrFN5O2/c1-16-13-22(32)30(15-21(31)27-20-8-7-17(24)14-19(20)25)23(26-16)29-11-9-28(10-12-29)18-5-3-2-4-6-18/h2-8,13-14H,9-12,15H2,1H3,(H,27,31)

InChI Key

MBWSGSOCAZZYAB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28996739

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

500.37

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.526

Distribution Coefficient, logD

3.518

Water Solubility, LogSw

-3.72

Polar Surface Area

54.668

Acid Dissociation Constant (pKa)

9.27

Base Dissociation Constant (pKb)

4.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

P194-1564 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with P194-1564 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P194-1564?
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What is the minimum amount of P194-1564 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P194-1564
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P194-1564
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P194-1564 available by request