P194-1580 Screening compound: N-(3,5-dimethylphenyl)-2-[4-methyl-6-oxo-2-(4-phenylpiperazin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide

P194-1580 Screening compound: N-(3,5-dimethylphenyl)-2-[4-methyl-6-oxo-2-(4-phenylpiperazin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide
P194-1580 Screening compound: N-(3,5-dimethylphenyl)-2-[4-methyl-6-oxo-2-(4-phenylpiperazin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P194-1580
N-(3,5-dimethylphenyl)-2-[4-methyl-6-oxo-2-(4-phenylpiperazin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P194-1580

Molecular Formula

C25H29N5O2 (C25 H29 N5 O2)

Compound Name

N-(3,5-dimethylphenyl)-2-[4-methyl-6-oxo-2-(4-phenylpiperazin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide

IUPAC name

N-(35-dimethylphenyl)-2-[4-methyl-6-oxo-2-(4-phenylpiperazin-1-yl)-16-dihydropyrimidin-1-yl]acetamide

SMILES

Cc1cc(NC(CN2C(N(CC3)CCN3c3ccccc3)=NC(C)=CC2=O)=O)cc(C)c1

InChI

InChI=1S/C25H29N5O2/c1-18-13-19(2)15-21(14-18)27-23(31)17-30-24(32)16-20(3)26-25(30)29-11-9-28(10-12-29)22-7-5-4-6-8-22/h4-8,13-16H,9-12,17H2,1-3H3,(H,27,31)

InChI Key

QXJOMGKAXCWBBQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29001885

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.538

Distribution Coefficient, logD

3.537

Water Solubility, LogSw

-3.61

Polar Surface Area

55.366

Acid Dissociation Constant (pKa)

13.31

Base Dissociation Constant (pKb)

4.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

P194-1580 in Drug Discovery

Included in Screening Libraries

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with P194-1580 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P194-1580?
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What is the minimum amount of P194-1580 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P194-1580
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P194-1580
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P194-1580 available by request