P194-1853 Screening compound: N-(3-chloro-2-methylphenyl)-2-[4,5-dimethyl-6-oxo-2-(piperidin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide

P194-1853 Screening compound: N-(3-chloro-2-methylphenyl)-2-[4,5-dimethyl-6-oxo-2-(piperidin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide
P194-1853 Screening compound: N-(3-chloro-2-methylphenyl)-2-[4,5-dimethyl-6-oxo-2-(piperidin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P194-1853
N-(3-chloro-2-methylphenyl)-2-[4,5-dimethyl-6-oxo-2-(piperidin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P194-1853

Molecular Formula

C20H25ClN4O2 (C20 H25 ClN4 O2)

Compound Name

N-(3-chloro-2-methylphenyl)-2-[4,5-dimethyl-6-oxo-2-(piperidin-1-yl)-1,6-dihydropyrimidin-1-yl]acetamide

IUPAC name

N-(3-chloro-2-methylphenyl)-2-[45-dimethyl-6-oxo-2-(piperidin-1-yl)-16-dihydropyrimidin-1-yl]acetamide

SMILES

Cc(c(NC(CN1C(N2CCCCC2)=NC(C)=C(C)C1=O)=O)ccc1)c1Cl

InChI

InChI=1S/C20H25ClN4O2/c1-13-15(3)22-20(24-10-5-4-6-11-24)25(19(13)27)12-18(26)23-17-9-7-8-16(21)14(17)2/h7-9H,4-6,10-12H2,1-3H3,(H,23,26)

InChI Key

VAIUSIHLPOJTPB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28996780

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.9

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.260

Distribution Coefficient, logD

3.260

Water Solubility, LogSw

-3.41

Polar Surface Area

50.926

Acid Dissociation Constant (pKa)

10.83

Base Dissociation Constant (pKb)

-0.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

P194-1853 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with P194-1853 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P194-1853?
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What is the minimum amount of P194-1853 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P194-1853
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P194-1853
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P194-1853 available by request