P196-1064 Screening compound: 2-[2-(4-chlorophenyl)-4-methyl-6-oxo-1,6-dihydropyrimidin-1-yl]-N-(2,5-dimethoxyphenyl)acetamide

P196-1064 Screening compound: 2-[2-(4-chlorophenyl)-4-methyl-6-oxo-1,6-dihydropyrimidin-1-yl]-N-(2,5-dimethoxyphenyl)acetamide
P196-1064 Screening compound: 2-[2-(4-chlorophenyl)-4-methyl-6-oxo-1,6-dihydropyrimidin-1-yl]-N-(2,5-dimethoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P196-1064
2-[2-(4-chlorophenyl)-4-methyl-6-oxo-1,6-dihydropyrimidin-1-yl]-N-(2,5-dimethoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P196-1064

Molecular Formula

C21H20ClN3O4 (C21 H20 ClN3 O4)

Compound Name

2-[2-(4-chlorophenyl)-4-methyl-6-oxo-1,6-dihydropyrimidin-1-yl]-N-(2,5-dimethoxyphenyl)acetamide

IUPAC name

2-[2-(4-chlorophenyl)-4-methyl-6-oxo-16-dihydropyrimidin-1-yl]-N-(25-dimethoxyphenyl)acetamide

SMILES

CC(N=C(c(cc1)ccc1Cl)N1CC(Nc(cc(cc2)OC)c2OC)=O)=CC1=O

InChI

InChI=1S/C21H20ClN3O4/c1-13-10-20(27)25(21(23-13)14-4-6-15(22)7-5-14)12-19(26)24-17-11-16(28-2)8-9-18(17)29-3/h4-11H,12H2,1-3H3,(H,24,26)

InChI Key

JFQPPRAKPKGABK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28996936

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.86

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.119

Distribution Coefficient, logD

3.119

Water Solubility, LogSw

-3.58

Polar Surface Area

63.109

Acid Dissociation Constant (pKa)

10.51

Base Dissociation Constant (pKb)

2.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

P196-1064 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

Bromodomain Modulators Library (5801 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Nervous system
  • Eye
Mechanism of action:
  • PPI modulators
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P196-1064 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P196-1064?
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What is the minimum amount of P196-1064 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P196-1064
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P196-1064
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P196-1064 available by request