P207-8883 Screening compound: 1-[5-(4-fluorophenyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxylic acid

P207-8883 Screening compound: 1-[5-(4-fluorophenyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxylic acid
P207-8883 Screening compound: 1-[5-(4-fluorophenyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound P207-8883
1-[5-(4-fluorophenyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P207-8883

Molecular Formula

C18H16FN3O2S (C18 H16 FN3 O2 S)

Compound Name

1-[5-(4-fluorophenyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxylic acid

IUPAC name

1-[5-(4-fluorophenyl)-[13]thiazolo[54-b]pyridin-2-yl]piperidine-4-carboxylic acid

SMILES

OC(C(CC1)CCN1c1nc2ccc(-c(cc3)ccc3F)nc2s1)=O

InChI

InChI=1S/C18H16FN3O2S/c19-13-3-1-11(2-4-13)14-5-6-15-16(20-14)25-18(21-15)22-9-7-12(8-10-22)17(23)24/h1-6,12H,7-10H2,(H,23,24)

InChI Key

HUGFDNKBGYMOFC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28897884

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.713

Distribution Coefficient, logD

1.160

Water Solubility, LogSw

-4.01

Polar Surface Area

50.336

Acid Dissociation Constant (pKa)

4.84

Base Dissociation Constant (pKb)

5.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

P207-8883 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Nervous system
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Ion Channels
  • Phosphatases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P207-8883 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P207-8883?
Check Price and Availability of P207-8883, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P207-8883 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P207-8883
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P207-8883
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P207-8883 available by request