P207-8947 Screening compound: 5-methoxy-1,2-dihydrospiro[indole-3,3'-pyrrolidin]-2-one

P207-8947 Screening compound: 5-methoxy-1,2-dihydrospiro[indole-3,3'-pyrrolidin]-2-one
P207-8947 Screening compound: 5-methoxy-1,2-dihydrospiro[indole-3,3'-pyrrolidin]-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P207-8947
5-methoxy-1,2-dihydrospiro[indole-3,3'-pyrrolidin]-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P207-8947

Molecular Formula

C12H14N2O2 (C12 H14 N2 O2)

Compound Name

5-methoxy-1,2-dihydrospiro[indole-3,3'-pyrrolidin]-2-one

IUPAC name

5-methoxy-12-dihydrospiro[indole-33'-pyrrolidin]-2-one

SMILES

COc(cc1)cc(C23CNCC3)c1NC2=O

InChI

InChI=1S/C12H14N2O2/c1-16-8-2-3-10-9(6-8)12(11(15)14-10)4-5-13-7-12/h2-3,6,13H,4-5,7H2,1H3,(H,14,15)/t12-/m0/s1

InChI Key

QUFRJMCKEIYCGV-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD24552024

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

218.26

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

0.972

Distribution Coefficient, logD

-2.712

Water Solubility, LogSw

-2.23

Polar Surface Area

45.204

Acid Dissociation Constant (pKa)

12.78

Base Dissociation Constant (pKb)

11.08

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.67

P207-8947 in Drug Discovery

Included in Screening Libraries

3D-Fragment Library (4274 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cardiovascular Library (22201 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Ion Channels Focused Library (26372 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Fragments
  • Cyclic compounds
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P207-8947 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P207-8947?
Check Price and Availability of P207-8947, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P207-8947 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P207-8947
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P207-8947
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P207-8947 available by request