P207-8975 Screening compound: 5-[(2-chlorophenyl)methyl]-3-[4-(pyrrolidin-3-yloxy)phenyl]-1,2,4-oxadiazole

P207-8975 Screening compound: 5-[(2-chlorophenyl)methyl]-3-[4-(pyrrolidin-3-yloxy)phenyl]-1,2,4-oxadiazole
P207-8975 Screening compound: 5-[(2-chlorophenyl)methyl]-3-[4-(pyrrolidin-3-yloxy)phenyl]-1,2,4-oxadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound P207-8975
5-[(2-chlorophenyl)methyl]-3-[4-(pyrrolidin-3-yloxy)phenyl]-1,2,4-oxadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P207-8975

Molecular Formula

C19H18ClN3O2 (C19 H18 ClN3 O2)

Compound Name

5-[(2-chlorophenyl)methyl]-3-[4-(pyrrolidin-3-yloxy)phenyl]-1,2,4-oxadiazole

IUPAC name

5-[(2-chlorophenyl)methyl]-3-[4-(pyrrolidin-3-yloxy)phenyl]-124-oxadiazole

SMILES

Clc1c(Cc2nc(-c(cc3)ccc3OC3CNCC3)no2)cccc1

InChI

InChI=1S/C19H18ClN3O2/c20-17-4-2-1-3-14(17)11-18-22-19(23-25-18)13-5-7-15(8-6-13)24-16-9-10-21-12-16/h1-8,16,21H,9-12H2/t16-/m0/s1

InChI Key

DXMJOQWJHWLLTH-INIZCTEOSA-N

MDL Number (MFCD)

MFCD28897989

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

355.82

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.279

Distribution Coefficient, logD

2.372

Water Solubility, LogSw

-4.52

Polar Surface Area

50.021

Acid Dissociation Constant (pKa)

26.46

Base Dissociation Constant (pKb)

9.30

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.30

P207-8975 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds
Agro:
  • Agro

References: we are preparing a list of scientific research reports with P207-8975 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P207-8975?
Check Price and Availability of P207-8975, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P207-8975 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P207-8975
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P207-8975
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P207-8975 available by request