P218-3150 Screening compound: 4-[(3-{2-[4-(trifluoromethyl)phenyl]-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine-5-carbonyl}-1,2-oxazol-5-yl)methyl]morpholine

P218-3150 Screening compound: 4-[(3-{2-[4-(trifluoromethyl)phenyl]-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine-5-carbonyl}-1,2-oxazol-5-yl)methyl]morpholine
P218-3150 Screening compound: 4-[(3-{2-[4-(trifluoromethyl)phenyl]-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine-5-carbonyl}-1,2-oxazol-5-yl)methyl]morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound P218-3150
4-[(3-{2-[4-(trifluoromethyl)phenyl]-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine-5-carbonyl}-1,2-oxazol-5-yl)methyl]morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P218-3150

Molecular Formula

C23H24F3N5O3 (C23 H24 F3 N5 O3)

Compound Name

4-[(3-{2-[4-(trifluoromethyl)phenyl]-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine-5-carbonyl}-1,2-oxazol-5-yl)methyl]morpholine

IUPAC name

4-[(3-{2-[4-(trifluoromethyl)phenyl]-4H5H6H7H8H-pyrazolo[15-a][14]diazepine-5-carbonyl}-12-oxazol-5-yl)methyl]morpholine

SMILES

O=C(c1noc(CN2CCOCC2)c1)N1Cc2cc(-c3ccc(C(F)(F)F)cc3)nn2CCC1

InChI

InChI=1S/C23H24F3N5O3/c24-23(25,26)17-4-2-16(3-5-17)20-12-18-14-30(6-1-7-31(18)27-20)22(32)21-13-19(34-28-21)15-29-8-10-33-11-9-29/h2-5,12-13H,1,6-11,14-15H2

InChI Key

DORKMYRKZNAAEC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31981756

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.996

Distribution Coefficient, logD

2.986

Water Solubility, LogSw

-3.15

Polar Surface Area

63.035

Acid Dissociation Constant (pKa)

27.26

Base Dissociation Constant (pKb)

5.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.48

P218-3150 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

KRAS-Targeted Library (16000 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • GPCR
  • Ion Channels
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with P218-3150 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P218-3150?
Check Price and Availability of P218-3150, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P218-3150 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P218-3150
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P218-3150
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P218-3150 available by request