P218-3467 Screening compound: 3-[2-(4-methoxyphenyl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine-5-carbonyl]-1-(pyrrolidine-1-sulfonyl)piperidine

P218-3467 Screening compound: 3-[2-(4-methoxyphenyl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine-5-carbonyl]-1-(pyrrolidine-1-sulfonyl)piperidine
P218-3467 Screening compound: 3-[2-(4-methoxyphenyl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine-5-carbonyl]-1-(pyrrolidine-1-sulfonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound P218-3467
3-[2-(4-methoxyphenyl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine-5-carbonyl]-1-(pyrrolidine-1-sulfonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P218-3467

Molecular Formula

C24H33N5O4S (C24 H33 N5 O4 S)

Compound Name

3-[2-(4-methoxyphenyl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine-5-carbonyl]-1-(pyrrolidine-1-sulfonyl)piperidine

IUPAC name

3-[2-(4-methoxyphenyl)-4H5H6H7H8H-pyrazolo[15-a][14]diazepine-5-carbonyl]-1-(pyrrolidine-1-sulfonyl)piperidine

SMILES

COc(cc1)ccc1-c1nn(CCCN(C2)C(C(CCC3)CN3S(N3CCCC3)(=O)=O)=O)c2c1

InChI

InChI=1S/C24H33N5O4S/c1-33-22-9-7-19(8-10-22)23-16-21-18-26(11-5-15-29(21)25-23)24(30)20-6-4-14-28(17-20)34(31,32)27-12-2-3-13-27/h7-10,16,20H,2-6,11-15,17-18H2,1H3/t20-/m0/s1

InChI Key

YKYKATNYGZMYAC-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD31992472

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.62

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.057

Distribution Coefficient, logD

2.057

Water Solubility, LogSw

-2.80

Polar Surface Area

72.377

Acid Dissociation Constant (pKa)

22.40

Base Dissociation Constant (pKb)

-0.87

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

58.33

P218-3467 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with P218-3467 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P218-3467?
Check Price and Availability of P218-3467, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P218-3467 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P218-3467
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P218-3467
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P218-3467 available by request