P227-1487 Screening compound: N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-4-[3-(3-METHOXYPHENYL)-1H-PYRAZOL-5-YL]-1-PIPERIDINECARBOXAMIDE

P227-1487 Screening compound: N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-4-[3-(3-METHOXYPHENYL)-1H-PYRAZOL-5-YL]-1-PIPERIDINECARBOXAMIDE
P227-1487 Screening compound: N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-4-[3-(3-METHOXYPHENYL)-1H-PYRAZOL-5-YL]-1-PIPERIDINECARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound P227-1487
N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-4-[3-(3-METHOXYPHENYL)-1H-PYRAZOL-5-YL]-1-PIPERIDINECARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P227-1487

Molecular Formula

C24H26N4O4 (C24 H26 N4 O4)

Compound Name

N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-4-[3-(3-METHOXYPHENYL)-1H-PYRAZOL-5-YL]-1-PIPERIDINECARBOXAMIDE

IUPAC name

n/a

SMILES

COc1cccc(-c2n[nH]c(C(CC3)CCN3C(Nc(cc3)cc4c3OCCO4)=O)c2)c1

InChI

InChI=1S/C24H26N4O4/c1-30-19-4-2-3-17(13-19)21-15-20(26-27-21)16-7-9-28(10-8-16)24(29)25-18-5-6-22-23(14-18)32-12-11-31-22/h2-6,13-16H,7-12H2,1H3,(H,25,29)(H,26,27)

InChI Key

DVGHZQOGSPJENF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27569953

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.344

Distribution Coefficient, logD

3.344

Water Solubility, LogSw

-3.43

Polar Surface Area

71.293

Acid Dissociation Constant (pKa)

12.72

Base Dissociation Constant (pKb)

3.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.33

P227-1487 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P227-1487 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P227-1487?
Check Price and Availability of P227-1487, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P227-1487 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P227-1487
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P227-1487
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P227-1487 available by request