P227-1988 Screening compound: 1-(4-methoxybenzenesulfonyl)-4-[3-(3-methoxyphenyl)-1H-pyrazol-5-yl]piperidine

P227-1988 Screening compound: 1-(4-methoxybenzenesulfonyl)-4-[3-(3-methoxyphenyl)-1H-pyrazol-5-yl]piperidine
P227-1988 Screening compound: 1-(4-methoxybenzenesulfonyl)-4-[3-(3-methoxyphenyl)-1H-pyrazol-5-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound P227-1988
1-(4-methoxybenzenesulfonyl)-4-[3-(3-methoxyphenyl)-1H-pyrazol-5-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P227-1988

Molecular Formula

C22H25N3O4S (C22 H25 N3 O4 S)

Compound Name

1-(4-methoxybenzenesulfonyl)-4-[3-(3-methoxyphenyl)-1H-pyrazol-5-yl]piperidine

IUPAC name

1-(4-methoxybenzenesulfonyl)-4-[3-(3-methoxyphenyl)-1H-pyrazol-5-yl]piperidine

SMILES

COc(cc1)ccc1S(N(CC1)CCC1c1cc(-c2cc(OC)ccc2)n[nH]1)(=O)=O

InChI

InChI=1S/C22H25N3O4S/c1-28-18-6-8-20(9-7-18)30(26,27)25-12-10-16(11-13-25)21-15-22(24-23-21)17-4-3-5-19(14-17)29-2/h3-9,14-16H,10-13H2,1-2H3,(H,23,24)

InChI Key

BPOGWAJDVLXZEJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27569980

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.322

Distribution Coefficient, logD

4.322

Water Solubility, LogSw

-4.27

Polar Surface Area

69.255

Acid Dissociation Constant (pKa)

13.91

Base Dissociation Constant (pKb)

3.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

P227-1988 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with P227-1988 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P227-1988?
Check Price and Availability of P227-1988, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P227-1988 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P227-1988
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P227-1988
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P227-1988 available by request