P244-0068 Screening compound: 7-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-6-phenyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one

P244-0068 Screening compound: 7-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-6-phenyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one
P244-0068 Screening compound: 7-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-6-phenyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P244-0068
7-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-6-phenyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P244-0068

Molecular Formula

C25H23FN4O2 (C25 H23 FN4 O2)

Compound Name

7-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-6-phenyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one

IUPAC name

7-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-6-phenyl-5H6H7H-pyrrolo[34-b]pyridin-5-one

SMILES

O=C(CC(c1ncccc1C1=O)N1c1ccccc1)N(CC1)CCN1c(cccc1)c1F

InChI

InChI=1S/C25H23FN4O2/c26-20-10-4-5-11-21(20)28-13-15-29(16-14-28)23(31)17-22-24-19(9-6-12-27-24)25(32)30(22)18-7-2-1-3-8-18/h1-12,22H,13-17H2/t22-/m0/s1

InChI Key

HPIRLSSYGQUXCC-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD27570110

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.088

Distribution Coefficient, logD

3.088

Water Solubility, LogSw

-3.60

Polar Surface Area

44.619

Acid Dissociation Constant (pKa)

21.17

Base Dissociation Constant (pKb)

4.77

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

24.00

P244-0068 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with P244-0068 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P244-0068?
Check Price and Availability of P244-0068, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P244-0068 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P244-0068
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P244-0068
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P244-0068 available by request