P257-0030 Screening compound: 5-[4-(4-ethylpiperazine-1-carbonyl)piperidin-1-yl]-N,N-dimethylpyrimidin-4-amine

P257-0030 Screening compound: 5-[4-(4-ethylpiperazine-1-carbonyl)piperidin-1-yl]-N,N-dimethylpyrimidin-4-amine
P257-0030 Screening compound: 5-[4-(4-ethylpiperazine-1-carbonyl)piperidin-1-yl]-N,N-dimethylpyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound P257-0030
5-[4-(4-ethylpiperazine-1-carbonyl)piperidin-1-yl]-N,N-dimethylpyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P257-0030

Molecular Formula

C18H30N6O (C18 H30 N6 O)

Compound Name

5-[4-(4-ethylpiperazine-1-carbonyl)piperidin-1-yl]-N,N-dimethylpyrimidin-4-amine

IUPAC name

5-[4-(4-ethylpiperazine-1-carbonyl)piperidin-1-yl]-NN-dimethylpyrimidin-4-amine

SMILES

CCN(CC1)CCN1C(C(CC1)CCN1c1c(N(C)C)ncnc1)=O

InChI

InChI=1S/C18H30N6O/c1-4-22-9-11-24(12-10-22)18(25)15-5-7-23(8-6-15)16-13-19-14-20-17(16)21(2)3/h13-15H,4-12H2,1-3H3

InChI Key

PWWVVFQUJUOEQZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27570339

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

346.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.770

Distribution Coefficient, logD

-0.111

Water Solubility, LogSw

-0.85

Polar Surface Area

46.593

Acid Dissociation Constant (pKa)

22.83

Base Dissociation Constant (pKb)

8.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

72.20

P257-0030 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P257-0030 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P257-0030?
Check Price and Availability of P257-0030, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P257-0030 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P257-0030
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P257-0030
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P257-0030 available by request