P257-0388 Screening compound: 5-{4-[4-(4-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-4-(pyrrolidin-1-yl)pyrimidine

P257-0388 Screening compound: 5-{4-[4-(4-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-4-(pyrrolidin-1-yl)pyrimidine
P257-0388 Screening compound: 5-{4-[4-(4-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-4-(pyrrolidin-1-yl)pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound P257-0388
5-{4-[4-(4-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-4-(pyrrolidin-1-yl)pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P257-0388

Molecular Formula

C24H31FN6O (C24 H31 FN6 O)

Compound Name

5-{4-[4-(4-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-4-(pyrrolidin-1-yl)pyrimidine

IUPAC name

5-{4-[4-(4-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-4-(pyrrolidin-1-yl)pyrimidine

SMILES

O=C(C(CC1)CCN1c1c(N2CCCC2)ncnc1)N(CC1)CCN1c(cc1)ccc1F

InChI

InChI=1S/C24H31FN6O/c25-20-3-5-21(6-4-20)28-13-15-31(16-14-28)24(32)19-7-11-29(12-8-19)22-17-26-18-27-23(22)30-9-1-2-10-30/h3-6,17-19H,1-2,7-16H2

InChI Key

QJHPBHROTXYYIJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27570447

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.145

Distribution Coefficient, logD

3.058

Water Solubility, LogSw

-2.92

Polar Surface Area

47.330

Acid Dissociation Constant (pKa)

21.94

Base Dissociation Constant (pKb)

6.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.20

P257-0388 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P257-0388 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P257-0388?
Check Price and Availability of P257-0388, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P257-0388 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P257-0388
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P257-0388
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P257-0388 available by request