P257-0595 Screening compound: 4-(piperidin-1-yl)-5-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyrimidine

P257-0595 Screening compound: 4-(piperidin-1-yl)-5-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyrimidine
P257-0595 Screening compound: 4-(piperidin-1-yl)-5-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound P257-0595
4-(piperidin-1-yl)-5-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P257-0595

Molecular Formula

C24H33N7O (C24 H33 N7 O)

Compound Name

4-(piperidin-1-yl)-5-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyrimidine

IUPAC name

4-(piperidin-1-yl)-5-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyrimidine

SMILES

O=C(C(CC1)CCN1c1c(N2CCCCC2)ncnc1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C24H33N7O/c32-24(31-16-14-29(15-17-31)22-6-2-3-9-26-22)20-7-12-28(13-8-20)21-18-25-19-27-23(21)30-10-4-1-5-11-30/h2-3,6,9,18-20H,1,4-5,7-8,10-17H2

InChI Key

BJBYYKNUJXAKIK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27570519

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.079

Distribution Coefficient, logD

2.975

Water Solubility, LogSw

-2.95

Polar Surface Area

55.475

Acid Dissociation Constant (pKa)

22.72

Base Dissociation Constant (pKb)

6.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

58.30

P257-0595 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P257-0595 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P257-0595?
Check Price and Availability of P257-0595, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P257-0595 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P257-0595
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P257-0595
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P257-0595 available by request