P257-0929 Screening compound: N~4~-(4-chloro-2-fluorophenyl)-1-(4-morpholino-5-pyrimidinyl)-4-piperidinecarboxamide

P257-0929 Screening compound: N~4~-(4-chloro-2-fluorophenyl)-1-(4-morpholino-5-pyrimidinyl)-4-piperidinecarboxamide
P257-0929 Screening compound: N~4~-(4-chloro-2-fluorophenyl)-1-(4-morpholino-5-pyrimidinyl)-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P257-0929
N~4~-(4-chloro-2-fluorophenyl)-1-(4-morpholino-5-pyrimidinyl)-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P257-0929

Molecular Formula

C20H23ClFN5O2 (C20 H23 ClFN5 O2)

Compound Name

N~4~-(4-chloro-2-fluorophenyl)-1-(4-morpholino-5-pyrimidinyl)-4-piperidinecarboxamide

IUPAC name

N-(4-chloro-2-fluorophenyl)-1-[4-(morpholin-4-yl)pyrimidin-5-yl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c1c(N2CCOCC2)ncnc1)Nc(ccc(Cl)c1)c1F

InChI

InChI=1S/C20H23ClFN5O2/c21-15-1-2-17(16(22)11-15)25-20(28)14-3-5-26(6-4-14)18-12-23-13-24-19(18)27-7-9-29-10-8-27/h1-2,11-14H,3-10H2,(H,25,28)

InChI Key

PLOBIQMKYHMDRB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27570597

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.89

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.936

Distribution Coefficient, logD

2.841

Water Solubility, LogSw

-3.43

Polar Surface Area

57.357

Acid Dissociation Constant (pKa)

8.39

Base Dissociation Constant (pKb)

6.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

P257-0929 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P257-0929 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P257-0929?
Check Price and Availability of P257-0929, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P257-0929 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P257-0929
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P257-0929
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P257-0929 available by request