P257-1123 Screening compound: N~4~-(2-chlorobenzyl)-1-[4-(4-methylpiperazino)-5-pyrimidinyl]-4-piperidinecarboxamide

P257-1123 Screening compound: N~4~-(2-chlorobenzyl)-1-[4-(4-methylpiperazino)-5-pyrimidinyl]-4-piperidinecarboxamide
P257-1123 Screening compound: N~4~-(2-chlorobenzyl)-1-[4-(4-methylpiperazino)-5-pyrimidinyl]-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P257-1123
N~4~-(2-chlorobenzyl)-1-[4-(4-methylpiperazino)-5-pyrimidinyl]-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P257-1123

Molecular Formula

C22H29ClN6O (C22 H29 ClN6 O)

Compound Name

N~4~-(2-chlorobenzyl)-1-[4-(4-methylpiperazino)-5-pyrimidinyl]-4-piperidinecarboxamide

IUPAC name

N-[(2-chlorophenyl)methyl]-1-[4-(4-methylpiperazin-1-yl)pyrimidin-5-yl]piperidine-4-carboxamide

SMILES

CN(CC1)CCN1c(ncnc1)c1N(CC1)CCC1C(NCc(cccc1)c1Cl)=O

InChI

InChI=1S/C22H29ClN6O/c1-27-10-12-29(13-11-27)21-20(15-24-16-26-21)28-8-6-17(7-9-28)22(30)25-14-18-4-2-3-5-19(18)23/h2-5,15-17H,6-14H2,1H3,(H,25,30)

InChI Key

YWXXMWUGQLAPFZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27570677

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.96

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.463

Distribution Coefficient, logD

1.986

Water Solubility, LogSw

-2.97

Polar Surface Area

54.945

Acid Dissociation Constant (pKa)

12.56

Base Dissociation Constant (pKb)

7.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

P257-1123 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P257-1123 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P257-1123?
Check Price and Availability of P257-1123, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P257-1123 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P257-1123
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P257-1123
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P257-1123 available by request