P257-1187 Screening compound: N-{2-[cyclohexyl(methyl)amino]ethyl}-1-[4-(4-methylpiperazin-1-yl)pyrimidin-5-yl]piperidine-4-carboxamide

P257-1187 Screening compound: N-{2-[cyclohexyl(methyl)amino]ethyl}-1-[4-(4-methylpiperazin-1-yl)pyrimidin-5-yl]piperidine-4-carboxamide
P257-1187 Screening compound: N-{2-[cyclohexyl(methyl)amino]ethyl}-1-[4-(4-methylpiperazin-1-yl)pyrimidin-5-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P257-1187
N-{2-[cyclohexyl(methyl)amino]ethyl}-1-[4-(4-methylpiperazin-1-yl)pyrimidin-5-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P257-1187

Molecular Formula

C24H41N7O (C24 H41 N7 O)

Compound Name

N-{2-[cyclohexyl(methyl)amino]ethyl}-1-[4-(4-methylpiperazin-1-yl)pyrimidin-5-yl]piperidine-4-carboxamide

IUPAC name

N-{2-[cyclohexyl(methyl)amino]ethyl}-1-[4-(4-methylpiperazin-1-yl)pyrimidin-5-yl]piperidine-4-carboxamide

SMILES

CN(CCNC(C(CC1)CCN1c1c(N2CCN(C)CC2)ncnc1)=O)C1CCCCC1

InChI

InChI=1S/C24H41N7O/c1-28-14-16-31(17-15-28)23-22(18-25-19-27-23)30-11-8-20(9-12-30)24(32)26-10-13-29(2)21-6-4-3-5-7-21/h18-21H,3-17H2,1-2H3,(H,26,32)

InChI Key

MDODAUXVTWKDDV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27570695

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.64

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.842

Distribution Coefficient, logD

0.105

Water Solubility, LogSw

-2.01

Polar Surface Area

57.824

Acid Dissociation Constant (pKa)

13.35

Base Dissociation Constant (pKb)

9.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

79.17

P257-1187 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with P257-1187 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P257-1187?
Check Price and Availability of P257-1187, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P257-1187 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P257-1187
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P257-1187
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P257-1187 available by request