P260-0101 Screening compound: 1-[4-(acetylamino)-5-pyrimidinyl]-N~4~-[3-(trifluoromethyl)benzyl]-4-piperidinecarboxamide

P260-0101 Screening compound: 1-[4-(acetylamino)-5-pyrimidinyl]-N~4~-[3-(trifluoromethyl)benzyl]-4-piperidinecarboxamide
P260-0101 Screening compound: 1-[4-(acetylamino)-5-pyrimidinyl]-N~4~-[3-(trifluoromethyl)benzyl]-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P260-0101
1-[4-(acetylamino)-5-pyrimidinyl]-N~4~-[3-(trifluoromethyl)benzyl]-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P260-0101

Molecular Formula

C20H22F3N5O2 (C20 H22 F3 N5 O2)

Compound Name

1-[4-(acetylamino)-5-pyrimidinyl]-N~4~-[3-(trifluoromethyl)benzyl]-4-piperidinecarboxamide

IUPAC name

1-(4-acetamidopyrimidin-5-yl)-N-{[3-(trifluoromethyl)phenyl]methyl}piperidine-4-carboxamide

SMILES

CC(Nc(ncnc1)c1N(CC1)CCC1C(NCc1cccc(C(F)(F)F)c1)=O)=O

InChI

InChI=1S/C20H22F3N5O2/c1-13(29)27-18-17(11-24-12-26-18)28-7-5-15(6-8-28)19(30)25-10-14-3-2-4-16(9-14)20(21,22)23/h2-4,9,11-12,15H,5-8,10H2,1H3,(H,25,30)(H,24,26,27,29)

InChI Key

UIPGPOFUOXLVBW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27570704

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.649

Distribution Coefficient, logD

0.843

Water Solubility, LogSw

-1.75

Polar Surface Area

71.985

Acid Dissociation Constant (pKa)

6.67

Base Dissociation Constant (pKb)

4.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

P260-0101 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with P260-0101 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P260-0101?
Check Price and Availability of P260-0101, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P260-0101 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P260-0101
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P260-0101
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P260-0101 available by request