P271-0164 Screening compound: 1-(4-methoxyphenyl)-4-(1-{pyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)piperazine

P271-0164 Screening compound: 1-(4-methoxyphenyl)-4-(1-{pyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)piperazine
P271-0164 Screening compound: 1-(4-methoxyphenyl)-4-(1-{pyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound P271-0164
1-(4-methoxyphenyl)-4-(1-{pyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P271-0164

Molecular Formula

C24H28N6O2 (C24 H28 N6 O2)

Compound Name

1-(4-methoxyphenyl)-4-(1-{pyrido[2,3-b]pyrazin-7-yl}piperidine-3-carbonyl)piperazine

IUPAC name

1-(4-methoxyphenyl)-4-(1-{pyrido[23-b]pyrazin-7-yl}piperidine-3-carbonyl)piperazine

SMILES

COc(cc1)ccc1N(CC1)CCN1C(C(CCC1)CN1c1cc2nccnc2nc1)=O

InChI

InChI=1S/C24H28N6O2/c1-32-21-6-4-19(5-7-21)28-11-13-29(14-12-28)24(31)18-3-2-10-30(17-18)20-15-22-23(27-16-20)26-9-8-25-22/h4-9,15-16,18H,2-3,10-14,17H2,1H3/t18-/m0/s1

InChI Key

AFCPGAHEUJFEFE-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27570790

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.236

Distribution Coefficient, logD

2.236

Water Solubility, LogSw

-2.53

Polar Surface Area

59.338

Acid Dissociation Constant (pKa)

22.59

Base Dissociation Constant (pKb)

4.50

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.70

P271-0164 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with P271-0164 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P271-0164?
Check Price and Availability of P271-0164, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P271-0164 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P271-0164
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P271-0164
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P271-0164 available by request